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Volume 9   Issue 2   Year 2014
Estimating the Time of Crossing a High, Long and Arbitrary Bumpy Free Energy Barrier

Finkelstein A.V.

Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region142290, Russia

afinkel@vega.protres.ru

Abstract. This communication presents a simple but rather general analytical estimate of the characteristic time of crossing a long, high and arbitrary bumpy free energy barrier in a course of sequential chemical, biochemical or physical reaction.

 
Key words: free energy of the barrier, time of crossing the barrier, polymerization, one-dimensional diffusion, quasistationary approximation, generalized quasistationary approximation, secondary structure formation, population of intermediate states.
Table of Contents Original Article
Math. Biol. Bioinf.
2014;9(2):518-526
doi: 10.17537/2014.9.518
published in Russian

Abstract (rus.)
Abstract (eng.)
Full text (rus., pdf)
References

 

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