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Volume 11   Issue 1   Year 2016
On the DNA Kink Motion Under the Action of Constant Torque

Yakushevich L.V., Balashova V.N., Zakiryanov F.K.

Institute of cell biophysics RAS, Pushchino, Moscow region, Russia
Bashkir State University, Ufa, Russia

Abstract. The influence of the torsion moment on the DNA kink motion is studied by the methods of mathematical modeling. Time dependence of the kink coordinate, velocity, size, and energy on the different values of the parameters of the external torsion moment have been found. It has been shown that by changing the parameters, by switching on and off of the external action, one could regulate the velocity and the direction of the kink movement. Estimation of the torque value necessary for the kink (open state) movement with the velocity comparable to the transcription velocity, has been made. 
 
Key words: DNA dynamics, angular oscillations of nitrous bases, torque, sine-Gordon equation, kink.
Table of Contents Original Article
Math. Biol. Bioinf.
2016;11(1):81-90
doi: 10.17537/2016.11.81
published in Russian

Abstract (rus.)
Abstract (eng.)
Full text (rus., pdf)
References

 

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