Russian version English version
Volume 8   Issue 2   Year 2013
Recognition and Stability Analysis of Structural Motifs of α-α-corner Type in Globular Proteins

Rudnev V.R., Pankratov A.N., Kulikova L.I., Dedus F.F., Tikhonov D.A., Efimov A.V.

Institite of Mathematical Problems of Biology of the Russian Academy of Sciences
Moscow State University
Institite of Protein Research of the Russian Academy of Sciences

Abstract. The problem of recognition of structural motifs of proteins is considered by the example of α-α-corners. We propose a hybrid approach to solving the problems of the analysis of the spatial structure of proteins based on an analytical description of the main chain of the protein globule and spectral method for detecting repetitions. We found 110 α-α-corners in the  PDB, corresponding to a given standard. The molecular dynamics method is shown that α-α-corners as autonomous entities stable in the aqueous medium.

Key words: pattern recognition, orthogonal polynomials, analytical description, super secondary structures of proteins.


Table of Contents Original Article
Math. Biol. Bioinf.
doi: 10.17537/2013.8.398
published in Russian

Abstract (rus.)
Abstract (eng.)
Full text (rus., pdf)


  Copyright IMPB RAS © 2005-2024