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Volume 3   Issue 1   Year 2008
Search of Regular Sequences in Promoters from Various Genomes Using Runs Test

Shelenkov A.A., Korotkov E.V.

Bioengineering Centre of Russian Academy of Sciences, Moscow, 117312, Russia

Abstract. In this paper, a notion of “regularity” is introduced to describe the structural features of DNA sequences. This notion expands the “latent periodicity” term. A novel method for revealing regularity based on the runs test is given. The search of regular sequences in eukaryotic promoters has shown that more than 60% of them possess the regularity property on statistically significant level. Possible biological functions of regularity are discussed together with possibility of using this characteristic for making promoter annotation.

Key words: regularity, promoters, DNA sequences.


Table of Contents Original Article
Math. Biol. Bioinf.
doi: 10.17537/2008.3.1
published in Russian

Abstract (rus.)
Abstract (eng.)
Full text (rus., pdf)


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