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Volume 5   Issue 2   Year 2010
Statistical Analysis and Prediction of Disordered Residues in Protein Structures

Lobanov M.Yu., Galzitskaya O.V.

Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region,  142290 Russia

Abstract. Statistical data of occurrences of disordered residues in the middle and termini parts of protein chain have been obtained. A new method based on the Ising model (model of two states) for prediction of disordered residues from protein sequence alone has been developed. Testing of the method by using two additional databases demonstrates that it ranks among the five best methods. 

Key words: disordered residues, Ising model, specificity, sensitivity.


Table of Contents Original Article
Math. Biol. Bioinf.
doi: 10.17537/2010.5.124
published in Russian

Abstract (rus.)
Abstract (eng.)
Full text (rus., pdf)


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